Doctor Octopus

Otto Gunther Octavius, feared as Doctor Octopus or simply "Doc Ock", is a genius German scientist and a former employee of OSCORP who worked with Peter's parents on the prototype of the Particle Accelerator program. Otto used tentacle-like harness to operate the machinery. Otto warned Norman Osborn of the dangers of the particle accelerator, but was ignored and ordered to continue his work, which ultimately led to the explosion of the particle accelerator and the aforementioned harness being permanently fused to Otto. Otto went around experimenting on and recruiting those affected by the explosion.